Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426005 | 0.91 | HCRTR1 (0.52) | HCRTR1HCRTR2USP2TSHRCYP2D6 | |
| SCHEMBL12626158 | 0.89 | LMNA (0.61) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL12626946 | 0.89 | HCRTR1 (0.53) | HCRTR1HCRTR2TSHRCYP2D6ALDH1A1 | |
| SCHEMBL12622076 | 0.85 | L3MBTL1 (0.52) | HCRTR1HCRTR2USP2TSHRALDH1A1 | |
| SCHEMBL12663594 | 0.85 | L3MBTL1 (0.52) | HCRTR1HCRTR2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL13035949 | 0.83 | L3MBTL1 (0.45) | HCRTR1HCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL12661174 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL12622002 | 0.82 | POLB (0.64) | HCRTR1HCRTR2USP2TSHRCYP2D6 | |
| SCHEMBL12626207 | 0.82 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL12626027 | 0.82 | ALDH1A1 (0.49) | HCRTR1HCRTR2TSHRCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | BURNS BARBIER LINDSAY | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | FLNA, OPRL1, FLNB | HCRTR1 1651/4885HCRTR2 1832/4885USP2 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.