Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621992 | 0.84 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1GAAHCRTR1HCRTR2 | |
| SCHEMBL13035959 | 0.83 | HCRTR1 (0.58) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12626045 | 0.80 | CHRM2 (0.49) | CHRM2CHRM3ALDH1A1 | |
| SCHEMBL12626490 | 0.78 | MMP1 (0.47) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12626946 | 0.75 | HCRTR1 (0.53) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12626158 | 0.75 | LMNA (0.61) | L3MBTL1ALDH1A1 | |
| SCHEMBL15426005 | 0.75 | HCRTR1 (0.52) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12663594 | 0.74 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12622076 | 0.74 | L3MBTL1 (0.52) | L3MBTL1CHRM2CHRM3ALDH1A1HCRTR1 | |
| SCHEMBL12626027 | 0.73 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | BURNS BARBIER LINDSAY | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | FLNA, OPRL1, FLNB | L3MBTL1 2361/4885CHRM2 610/4885CHRM3 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.