Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729361 | 0.78 | ALDH1A1 (0.56) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL366128 | 0.75 | ALDH1A1 (0.64) | SLC6A3SLC6A2KDM4ECHRM2ADRA2B | |
| SCHEMBL7094986 | 0.71 | KDM4E (0.50) | ALPGSLC6A3SLC6A2KDM4EGAA | |
| SCHEMBL7523284 | 0.71 | KDM4E (0.50) | SLC6A3SLC6A2KDM4EGAARECQL | |
| SCHEMBL7094989 | 0.71 | KDM4E (0.50) | ALPGSLC6A3SLC6A2KDM4EGAA | |
| SCHEMBL15389372 | 0.70 | CHRM2 (0.68) | ALPLALPGSLC6A3SLC6A2CHRM2 | |
| SCHEMBL1755597 | 0.70 | ALOX15 (0.47) | ALPLALPGSLC6A3SLC6A2KDM4E | |
| SCHEMBL10042343 | 0.70 | KDM4E (0.65) | ALPLALPGSLC6A3SLC6A2KDM4E | |
| SCHEMBL10541477 | 0.69 | ALPL (0.64) | ALPLALPGKDM4EGAACHRM2 | |
| SCHEMBL21648644 | 0.69 | TDP1 (0.56) | ALPLALPGSLC6A3KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266968-A2 | Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors | GENZYME CORPORATION (US) | 2010-12-29 | — | — | EP | disclosed |