Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 13/20 | 0.55 |
| ▸ | NOS1 | P29475 | 11/20 | 0.55 |
| ▸ | NOS3 | P29474 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040653 | 0.94 | NOS2 (0.55) | NOS2NOS1NOS3 | |
| SCHEMBL13040665 | 0.90 | NOS2 (0.42) | NOS2NOS1NOS3 | |
| SCHEMBL6166695 | 0.86 | NOS2 (0.45) | NOS2NOS1NOS3 | |
| SCHEMBL8329772 | 0.84 | NOS2 (0.39) | NOS2NOS1NOS3 | |
| SCHEMBL8330518 | 0.83 | NOS2 (0.40) | NOS2NOS1NOS3 | |
| SCHEMBL6164525 | 0.83 | NOS2 (0.39) | NOS2NOS1NOS3 | |
| SCHEMBL8328137 | 0.82 | NOS2 (0.51) | NOS2NOS1NOS3 | |
| SCHEMBL6167004 | 0.82 | NOS2 (0.38) | NOS2NOS1NOS3 | |
| SCHEMBL8330353 | 0.82 | NOS2 (0.38) | NOS2NOS1NOS3 | |
| SCHEMBL13040655 | 0.82 | NOS2 (0.38) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | NOS2, NOS3, NOS1 | NOS2 1/4885NOS1 3/4885NOS3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.