SCHEMBL1304102

SCHEMBL1304102

CCCCCCCCCCCC(=O)NC(CCO)[N+](C)(C)C(CCO)(CCCS(=O)(=O)O)C(=O)[O-]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.38
CPT1A P50416 1/20 0.38
CPT1B Q92523 1/20 0.38
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
FAAH O00519 2/20 0.35
MAPK1 P28482 1/20 0.35
NOD1 Q9Y239 2/20 0.33
PLA2G2C Q5R387 1/20 0.33
DNM1 Q05193 1/20 0.33
GAA P10253 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
PLA2G1B P04054 1/20 0.32
PLA2G2A P14555 1/20 0.32
DEGS1 O15121 1/20 0.32
PLA2G10 O15496 2/20 0.32
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8524200 0.87 EPHX2 (0.34)
SCHEMBL1177056 0.83 PLA2G2C (0.41) CPT2CPT1ACPT1BMEN1KMT2A
SCHEMBL127781 0.81 TP53 (0.32) PLA2G1B
SCHEMBL9536909 0.76 CPT2 (0.47) CPT2CPT1ACPT1BMEN1KMT2A
SCHEMBL7558816 0.75
SCHEMBL1304197 0.74 FAAH (0.42) CPT2CPT1ACPT1BMEN1KMT2A
SCHEMBL11133656 0.72
SCHEMBL11442881 0.72 EPHX2 (0.36)
SCHEMBL11128106 0.71 EPHX2 (0.38) FAAH
SCHEMBL3830783 0.71 DNM1 (0.34) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765912-B1 PYRROLIDONE-CARBOXYLIC MODIFIED POLYSILOXANES HAVING AQUEOUS AND DETERGENT SOLUBILITIES AND WATER-IN-OIL EMULSION CAPABILITY CRODA AMERICAS LLC (US) 2015-03-25 EP disclosed
EP-2222393-B1 METHOD FOR PRODUCING OIL-IN-WATER EMULSIONS FROM SELF-EMULSIFYING GEL CONCENTRATES SASOL GERMANY GMBH (DE) 2014-09-10 EP disclosed
EP-2222394-B1 METHOD OF PRODUCING WAX IN WATER DISPERSIONS OF SELF-EMULSIFYING GEL CONCENTRATES SASOL GERMANY GMBH (DE) 2013-11-13 EP disclosed
US-8053513-B2 enhanced water and detergent solubility with increased number of pyrrolidone groups in the polysiloxane; reacting itaconic acid with a polysiloxane having an aminoalkylsilandiol monomer; enhanced compatibility with electrolyte, silicone oil and hydrocarbons, and cleansing properties; sunscreen UNIQEMA AMERICAS LLC (US) 2011-11-08 US disclosed
EP-2222394-A1 METHOD OF PRODUCING WAX IN WATER DISPERSIONS OF SELF-EMULSIFYING GEL CONCENTRATES SASOL Germany GmbH (DE) 2010-09-01 EP disclosed
WO-2009079995-A1 METHOD OF PRODUCING WAX IN WATER DISPERSIONS OF SELF-EMULSIFYING GEL CONCENTRATES SASOL GERMANY GMBH (DE) 2009-07-02 WO disclosed
US-20080138301-A1 Pyrrolidone-Carboxylic Modified Polysiloxanes Having Aqueous and Detergent Solubilities and Water-In-Oil Emulsion Capability CRODA UNIQEMA INC. (US) 2008-06-12 US disclosed
EP-1395644-B1 MIXED POLYALKYLENE GLYCOL HYDROXYALKYL ISOSTEARAMIDES AS RHEOLOGY ADJUVANTS CRODA UNIQEMA INC (US) 2008-06-04 EP disclosed
US-20070277906-A1 Water-Based Metal Treatment Composition MIDDLESEX SILVER CO., LIMITED (GB) 2007-12-06 US disclosed
US-7214650-B2 Detergent compositions comprising polymeric suds enhancers which have improved mildness and skin feel THE PROCTER & GAMBLE CO. (US) 2007-05-08 US disclosed
WO-1998024402-A1 HAIR CONDITIONING COMPOSITIONS COMPRISING WATER-INSOLUBLE HIGH MOLECULAR WEIGHT OILY COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1998-06-11 WO disclosed
WO-1998019655-A1 HAIR CONDITIONING COMPOSITION COMPRISING SILICONE EMULSION THE PROCTER & GAMBLE COMPANY (US) 1998-05-14 WO disclosed
WO-1998019654-A1 HAIR MOUSSE COMPOSITION COMPRISING SILICONE EMULSION THE PROCTER & GAMBLE COMPANY (US) 1998-05-14 WO disclosed
WO-1998018435-A2 CONDITIONING SHAMPOO COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-05-07 WO disclosed
WO-1998018443-A1 CONDITIONING SHAMPOO COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-05-07 WO disclosed
WO-1998016189-A1 CONDITIONING SHAMPOO COMPOSITIONS HAVING IMPROVED SILICONE DEPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-04-23 WO disclosed
EP-0659071-B1 MILD, SUBSTANTIALLY COLORLESS SHAMPOO COMPOSITION PROCTER & GAMBLE (US) 1997-10-15 EP disclosed
US-5632978-A Mild shower gel composition comprising fatty alcohol which imparts improved lathering and thickening properties THE PROCTER & GAMBLE COMPANY (US) 1997-05-27 US disclosed
US-5607678-A COMPRISING ANIONIC AND AMPHOTERIC SURFACTANTS; IMPROVED LATHERING AND RINSING THE PROCTER & GAMBLE COMPANY (US) 1997-03-04 US disclosed
US-3950417-A A BETAINE AMPHOTERIC SURFACTANT, ANIONIC SURFACTANTS, NONIONIC SURFACTANTS JOHNSON & JOHNSON (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138301-A1 Pyrrolidone-Carboxylic Modified Polysiloxanes Having Aqueous and Detergent Solubilities and Water-In-Oil Emulsion Capability COPE, PLOD1, ELOVL1 CPT2 4010/4885CPT1A 2419/4885CPT1B 2428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.