Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303483 | 0.80 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1CPT2 | |
| SCHEMBL98039 | 0.80 | CA2 (0.37) | MEN1KMT2ALMNAPOLBGRK2 | |
| SCHEMBL8983862 | 0.80 | CA2 (0.37) | MEN1KMT2ALMNAPOLBGRK2 | |
| SCHEMBL9188125 | 0.80 | CA2 (0.37) | MEN1KMT2ALMNAPOLBGRK2 | |
| SCHEMBL1304438 | 0.80 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1CPT2 | |
| SCHEMBL3829582 | 0.77 | CA2 (0.36) | — | |
| SCHEMBL99789 | 0.74 | CA2 (0.38) | MEN1KMT2ALMNAPOLBGRK2 | |
| SCHEMBL11449224 | 0.74 | EPHX2 (0.39) | MEN1KMT2ACPT2CPT1ACPT1B | |
| SCHEMBL16266150 | 0.74 | EPHX2 (0.39) | MEN1KMT2ACPT2CPT1ACPT1B | |
| SCHEMBL1304102 | 0.74 | CPT2 (0.38) | FAAHMEN1KMT2AMAPK1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765912-B1 | PYRROLIDONE-CARBOXYLIC MODIFIED POLYSILOXANES HAVING AQUEOUS AND DETERGENT SOLUBILITIES AND WATER-IN-OIL EMULSION CAPABILITY | CRODA AMERICAS LLC (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2222393-B1 | METHOD FOR PRODUCING OIL-IN-WATER EMULSIONS FROM SELF-EMULSIFYING GEL CONCENTRATES | SASOL GERMANY GMBH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2222394-B1 | METHOD OF PRODUCING WAX IN WATER DISPERSIONS OF SELF-EMULSIFYING GEL CONCENTRATES | SASOL GERMANY GMBH (DE) | 2013-11-13 | — | — | EP | disclosed |
| US-8053513-B2 | enhanced water and detergent solubility with increased number of pyrrolidone groups in the polysiloxane; reacting itaconic acid with a polysiloxane having an aminoalkylsilandiol monomer; enhanced compatibility with electrolyte, silicone oil and hydrocarbons, and cleansing properties; sunscreen | UNIQEMA AMERICAS LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-20080138301-A1 | Pyrrolidone-Carboxylic Modified Polysiloxanes Having Aqueous and Detergent Solubilities and Water-In-Oil Emulsion Capability | CRODA UNIQEMA INC. (US) | 2008-06-12 | — | — | US | disclosed |
| EP-1395644-B1 | MIXED POLYALKYLENE GLYCOL HYDROXYALKYL ISOSTEARAMIDES AS RHEOLOGY ADJUVANTS | CRODA UNIQEMA INC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-20070277906-A1 | Water-Based Metal Treatment Composition | MIDDLESEX SILVER CO., LIMITED (GB) | 2007-12-06 | — | — | US | disclosed |
| US-7214650-B2 | Detergent compositions comprising polymeric suds enhancers which have improved mildness and skin feel | THE PROCTER & GAMBLE CO. (US) | 2007-05-08 | — | — | US | disclosed |
| EP-1765912-A1 | PYRROLIDONE-CARBOXYLIC MODIFIED POLYSILOXANES HAVING AQUEOUS AND DETERGENT SOLUBILITIES AND WATER-IN-OIL EMULSION CAPABILITY | Croda Uniqema Inc (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20070039665-A1 | Enhancing silver tarnish-resistance | MIDDLESEX SILVER CO. LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| WO-1997014396-A1 | CONDITIONING SHAMPOO COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-24 | — | — | WO | disclosed |
| US-5607678-A | COMPRISING ANIONIC AND AMPHOTERIC SURFACTANTS; IMPROVED LATHERING AND RINSING | THE PROCTER & GAMBLE COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0730442-A1 | ULTRA MILD LATHERING PERSONAL CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1996021426-A1 | THREE IN ONE ULTRA MILD LATHERING ANTIBACTERIAL LIQUID PERSONAL CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |
| EP-0706366-A1 | CONDITIONING SHAMPOOS CONTAINING POLYVALENT METAL CATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1996005798-A1 | MILD SHOWER GEL COMPOSITION COMPRISING FATTY ALCOHOL WHICH IMPARTS IMPROVED LATHERING AND THICKENING PROPERTIES | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-29 | — | — | WO | disclosed |
| WO-1995015150-A2 | ULTRA MILD LATHERING PERSONAL CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1995-06-08 | — | — | WO | disclosed |
| WO-1995001152-A1 | CONDITIONING SHAMPOOS CONTAINING POLYVALENT METAL CATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-01-12 | — | — | WO | disclosed |
| WO-1994005256-A1 | MILD, SUBSTANTIALLY COLORLESS SHAMPOO COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-17 | — | — | WO | disclosed |
| US-3950417-A | A BETAINE AMPHOTERIC SURFACTANT, ANIONIC SURFACTANTS, NONIONIC SURFACTANTS | JOHNSON & JOHNSON (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138301-A1 | Pyrrolidone-Carboxylic Modified Polysiloxanes Having Aqueous and Detergent Solubilities and Water-In-Oil Emulsion Capability | COPE, PLOD1, ELOVL1 | FAAH 358/4885MEN1 4266/4885KMT2A 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.