Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041380 | 0.89 | KDM4E (0.38) | APPTRPM8MAPT | |
| SCHEMBL13041360 | 0.87 | RAB9A (0.41) | TRPM8PTGS2MEN1MAPTKMT2A | |
| SCHEMBL13041470 | 0.81 | KDM4E (0.39) | MAPTPKM | |
| SCHEMBL13041466 | 0.80 | ABL1 (0.33) | PTGS2MAPT | |
| SCHEMBL13041383 | 0.76 | APEX1 (0.35) | MAPT | |
| SCHEMBL10238020 | 0.75 | PTGS2 (0.41) | DCKAPPTRPM8PTGS2MAPT | |
| SCHEMBL13041464 | 0.74 | ALDH1A1 (0.38) | PTGS2MEN1MAPTKMT2APKM | |
| SCHEMBL2762944 | 0.74 | RAB9A (0.41) | TRPM8MEN1MAPTKMT2A | |
| SCHEMBL13041400 | 0.73 | RAB9A (0.40) | TRPM8MEN1MAPTKMT2APKM | |
| SCHEMBL13041406 | 0.73 | NPC1 (0.36) | APPPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956999-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-02-17 | — | — | US | disclosed |
| US-8956999-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-02-17 | — | — | US | disclosed |
| EP-2173727-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2013-11-06 | — | — | EP | disclosed |
| US-20100279868-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100279868-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2009000533-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279868-A1 | NOVEL HERBICIDES | DDT, HPD, HSD17B1 | DCK 3337/4885APP 2798/4885TRPM8 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.