Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041483 | 0.88 | PTGDR2 (0.37) | DCKPTGDR2TP53MAPTLMNA | |
| SCHEMBL2762937 | 0.88 | HRH3 (0.41) | PTGDR2TRPM8MEN1KMT2AMAPT | |
| SCHEMBL13986201 | 0.88 | L3MBTL1 (0.33) | DCKPTGDR2 | |
| SCHEMBL13041543 | 0.88 | L3MBTL1 (0.44) | PTGDR2TRPM8KMT2AMAPT | |
| SCHEMBL13041549 | 0.87 | NPC1 (0.41) | MEN1KMT2AMAPTFFAR1 | |
| SCHEMBL13041530 | 0.86 | DCK (0.32) | DCKPTGDR2KMT2A | |
| SCHEMBL13041477 | 0.85 | PTPN11 (0.35) | DCKGRM2 | |
| SCHEMBL13041513 | 0.85 | RAB9A (0.36) | PTGDR2MEN1KMT2ATP53MAPT | |
| SCHEMBL13041555 | 0.84 | GRM2 (0.34) | GRM2 | |
| SCHEMBL13041551 | 0.83 | PTPN11 (0.39) | PTGDR2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956999-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-02-17 | — | — | US | disclosed |
| US-8956999-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-02-17 | — | — | US | disclosed |
| EP-2173727-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2013-11-06 | — | — | EP | disclosed |
| US-20100279868-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100279868-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2009000533-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279868-A1 | NOVEL HERBICIDES | DDT, HPD, HSD17B1 | DCK 3337/4885PTGDR2 865/4885TRPM8 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.