Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24287394 | 0.89 | SOS1 (0.55) | RAB9ASMN1; SMN2NPC1HTTSOS1 | |
| SCHEMBL21468597 | 0.88 | SOS1 (0.53) | RAB9ASMN1; SMN2NPC1HTTSOS1 | |
| SCHEMBL5536106 | 0.80 | SOS1 (0.54) | RAB9ASMN1; SMN2NPC1HTTSOS1 | |
| SCHEMBL1336716 | 0.80 | MAPT (0.62) | RAB9ASMN1; SMN2NPC1HTTMAPK14 | |
| SCHEMBL28934051 | 0.80 | GAA (0.65) | SMN1; SMN2HTTSOS1MAPK14GAA | |
| SCHEMBL18434217 | 0.80 | L3MBTL1 (0.54) | RAB9ASMN1; SMN2NPC1HTTGAA | |
| SCHEMBL15791720 | 0.80 | GAA (0.65) | RAB9ASMN1; SMN2NPC1HTTMAPK14 | |
| SCHEMBL7169368 | 0.80 | CYP3A4 (0.52) | RAB9ASMN1; SMN2NPC1HTTMAPK14 | |
| SCHEMBL28924001 | 0.80 | SOS1 (0.63) | RAB9ASMN1; SMN2NPC1HTTSOS1 | |
| SCHEMBL28689644 | 0.80 | LMNA (0.61) | RAB9ASMN1; SMN2NPC1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170117-A1 | MODULATORS OF ACKR3 AND USES THEREOF | INTERAX BIOTECH AG (CH) | 2025-05-29 | — | — | US | disclosed |
| EP-4486739-A1 | MODULATORS OF ACKR3 AND USES THEREOF | InterAx Biotech AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023166190-A1 | MODULATORS OF ACKR3 AND USES THEREOF | INTERAX BIOTECH AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| EP-2231680-B1 | LIGANDS FOR TRANSITION-METAL-CATALYZED CROSS-COUPLINGS, AND METHODS OF USE THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-03-28 | — | — | EP | disclosed |
| US-7858784-B2 | Ligands for transition-metal-catalyzed cross-couplings, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-28 | — | — | US | disclosed |
| US-20090221820-A1 | Ligands for Transition-Metal-Catalyzed Cross-Couplings, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170117-A1 | MODULATORS OF ACKR3 AND USES THEREOF | ACKR3, PROKR2, PROKR1 | RAB9A 1031/4885SMN1; SMN2 4495/4885NPC1 2082/4885 |
| US-20090221820-A1 | Ligands for Transition-Metal-Catalyzed Cross-Couplings, and Methods of Use Thereof | SOD1, TIMCC, TST | RAB9A 2626/4885SMN1; SMN2 3652/4885NPC1 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.