Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.72 |
| ▸ | ELANE | P08246 | 5/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.67 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.65 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.61 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13682905 | 1.00 | ACHE (0.72) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol C SCHEMBL16105580 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol C SCHEMBL29375168 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol C SCHEMBL7796382 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol C SCHEMBL910203 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL13682902 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol C SCHEMBL16105581 | 0.93 | ELANE (0.76) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL12942401 | 0.91 | ELANE (0.73) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL13043320 | 0.90 | PDE4D (0.81) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL17626656 | 0.88 | ACHE (0.80) | ACHEPTGS2TP53MDM2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9457007-B2 | Prenylflavanone compounds for modulating diabetes | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2016-10-04 | — | — | US | disclosed |
| US-9370503-B1 | Compounds for treating ocular diseases | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2016-06-21 | — | — | US | disclosed |
| US-20140296543-A1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2014-10-02 | — | — | US | disclosed |
| US-7829591-B2 | Flavanone compound and uses thereof | POKKA CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |
| US-7256214-B2 | 5,7,3',4'-Tetrahydroxy-5'-C-geranylflavanone (isonymphaeol-B), isolated from an Okinawa propolis; microbiocide, antitumor agent, food, beverage and cosmetic preservative; antioxidant food supplement | POKKA CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20070161579-A1 | FLAVANONE COMPOUND AND USES THEREOF | POKKA CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296543-A1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | SREBF2, GID4, SREBF1 | ACHE 4566/4885PTGS2 559/4885TP53 3763/4885 |
| US-20070161579-A1 | FLAVANONE COMPOUND AND USES THEREOF | NQO1, GPX4, NDUFV2 | ACHE 565/4885PTGS2 2072/4885TP53 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.