Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044596 | 0.92 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13044029 | 0.88 | NPC1 (0.56) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13044035 | 0.84 | RAB9A (0.58) | MEN1KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL13043196 | 0.82 | RAB9A (0.51) | MEN1KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL13044607 | 0.81 | GABRP (0.56) | MEN1KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL13043506 | 0.80 | RAB9A (0.71) | MEN1KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL13044046 | 0.78 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1558891 | 0.78 | ALDH1A1 (0.69) | MAPTALDH1A1KMT2ALMNANR4A2 | |
| SCHEMBL13044443 | 0.78 | RAB9A (0.46) | MEN1KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL13044604 | 0.77 | NR4A2 (0.60) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |