Acetyltryptophan

Acetyltryptophan

SCHEMBL1304487

CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.[K]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.77
ACE P12821 3/20 0.72
ITGB2 P05107 3/20 0.69
ICAM1 P05362 3/20 0.69
ITGAL P20701 3/20 0.69
TACR1 P25103 1/20 0.68
ECE1 P42892 6/20 0.66
KDM4E B2RXH2 1/20 0.63
APAF1 O14727 1/20 0.63
POLB P06746 1/20 0.63
MAPT P10636 1/20 0.63
RECQL P46063 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
FPR2 P25090 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyltryptophan SCHEMBL57141 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL29360698 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL29401158 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL702442 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL4216450 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL4216452 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL57140 0.99 ALOX15 (0.79) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL23933298 0.97 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL1427071 0.97 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL
Acetyltryptophan SCHEMBL1304483 0.97 ALOX15 (0.77) ALOX15ACEITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4139438-A1 COMPOSITIONS FOR PRESERVATION OF VIRAL VECTORS Cellular Biomedicine Group Inc. (US) 2023-03-01 EP disclosed
EP-1669065-B1 DRUG CONTAINING (2R)-2-PROPYLOCTANOIC ACID AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2012-07-18 EP disclosed
US-8053599-B2 Drug containing (2R)-2-propyloctanoic acid as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2011-11-08 US disclosed
US-20070105956-A1 Drug containing (2r)-2-propyloctanoic acid as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-10 US disclosed
US-20070066686-A1 Infusion preparation containing (2r)-2-propyloctanoic acid as at the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2007-03-22 US disclosed
EP-1669065-A1 DRUG CONTAINING (2R)-2-PROPYLOCTANOIC ACID AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-14 EP disclosed
EP-1669066-A1 INFUSION PREPARATION CONTAINING (2R)-2-PROPYLOCTANOIC ACID AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105956-A1 Drug containing (2r)-2-propyloctanoic acid as the active ingredient PSEN2, PRNP, GRIK5 ALOX15 74/4885ACE 1292/4885ITGB2 3855/4885
US-20070066686-A1 Infusion preparation containing (2r)-2-propyloctanoic acid as at the active ingredient PARK7, IDE, ATP6V1B2 ALOX15 19/4885ACE 1990/4885ITGB2 3282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.