Sugi Predict

Sugi Predict / Compounds / SCHEMBL13044882

SCHEMBL13044882

SCHEMBL13044882

Oc1c(-c2ccccc2)cccc1-c1ccccc1SCCSc1ccccc1-c1cccc(-c2ccccc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR7 P34969 3/20 0.53
▸ HNF4A P41235 1/20 0.44
▸ HDAC4 P56524 1/20 0.44
▸ HDAC2 Q92769 1/20 0.44
▸ HDAC8 Q9BY41 1/20 0.44
▸ HDAC6 Q9UBN7 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.41
▸ HPGD P15428 2/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ BCL2L1 Q07817 1/20 0.41
▸ BACE1 P56817 2/20 0.38
▸ MAPK1 P28482 2/20 0.37
▸ PDCD1 Q15116 1/20 0.37
▸ CD274 Q9NZQ7 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ APAF1 O14727 1/20 0.37
▸ MAP2K7 O14733 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ GMNN O75496 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13044904 0.93 HTR7 (0.50) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13043630 0.93 HTR7 (0.50) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13043680 0.86 HTR7 (0.42) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13045204 0.83 HNF4A (0.48) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13044418 0.83 HTR7 (0.44) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13044389 0.82 POLB (0.41) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13044027 0.81 HNF4A (0.47) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13044387 0.81 HTR7 (0.39) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL13043635 0.81 MPO (0.39) HTR7HNF4AHDAC4HDAC2HDAC8
SCHEMBL18181770 0.81 HTR7 (0.43) HTR7HNF4AHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689314-B2 Methods for preparing bridged bi-aromatic ligands UNIVATION TECHNOLOGIES, LLC (US) 2020-06-23 — — US disclosed
EP-3632920-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS Univation Technologies, LLC (US) 2020-04-08 — — EP disclosed
US-10239809-B2 Methods for preparing bridged bi-aromatic ligands UNIVATION TECHNOLOGIES, LLC (US) 2019-03-26 — — US disclosed
US-20180141883-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2018-05-24 — — US disclosed
US-20180141883-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2018-05-24 — — US disclosed
US-20180079704-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2018-03-22 — — US disclosed
US-20180079704-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2018-03-22 — — US disclosed
WO-2016172044-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2016-10-27 — — WO disclosed
WO-2016172114-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS UNIVATION TECHNOLOGIES, LLC (US) 2016-10-27 — — WO disclosed
EP-1501840-B1 BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM SYMYX SOLUTIONS INC (US) 2010-12-22 — — EP disclosed
US-7659415-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX SOLUTIONS, INC. (US) 2010-02-09 — — US disclosed
US-7659415-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX SOLUTIONS, INC. (US) 2010-02-09 — — US disclosed
US-20080269470-A1 Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom SYMYX TECHNOLOGIES, INC. (US) 2008-10-30 — — US disclosed
US-20080269470-A1 Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom SYMYX TECHNOLOGIES, INC. (US) 2008-10-30 — — US disclosed
US-7241715-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 — — US disclosed
US-7241715-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079704-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS AOC1, TYR, DDT HTR7 1106/4885HNF4A 2260/4885HDAC4 1862/4885
US-20080269470-A1 Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom WEE1, WASF2, WEE2 HTR7 935/4885HNF4A 3827/4885HDAC4 4228/4885
US-10689314-B2 Methods for preparing bridged bi-aromatic ligands TYR, AOC2, BICRA HTR7 611/4885HNF4A 1912/4885HDAC4 1607/4885
US-10239809-B2 Methods for preparing bridged bi-aromatic ligands AOC1, TYR, DDT HTR7 1106/4885HNF4A 2260/4885HDAC4 1862/4885
US-20180141883-A1 METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS TYR, AOC2, BICRA HTR7 611/4885HNF4A 1912/4885HDAC4 1607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.