Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12353756 | 0.78 | BRD4 (0.37) | — | |
| SCHEMBL12353759 | 0.78 | — | — | |
| SCHEMBL12353753 | 0.78 | — | — | |
| SCHEMBL5429208 | 0.77 | GBA1 (0.42) | PER2SIGMAR1 | |
| SCHEMBL16317736 | 0.77 | ALDH1A1 (0.35) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3370155 | 0.77 | PER2 (0.38) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11488636 | 0.75 | PER2 (0.38) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11472539 | 0.75 | PER2 (0.40) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11470312 | 0.75 | PER2 (0.38) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3927559 | 0.74 | CHRM2 (0.38) | PER2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292293-A1 | THERAPEUTIC SUBSTITUTED LACTAMS | OLD DAVID W | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292293-A1 | THERAPEUTIC SUBSTITUTED LACTAMS | MRPL21, TUBB6, GOT1 | PER2 3285/4885CHRM2 4260/4885CHRM4 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.