Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.50 |
| ▸ | MLYCD | O95822 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125247 | 0.78 | MAPT (0.48) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL131990 | 0.76 | NR1H2 (0.68) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL428959 | 0.74 | MLYCD (0.77) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL13046003 | 0.74 | MAPT (0.41) | NR1H2NR1H3KDM4EALDH1A1MAPT | |
| Water SCHEMBL1684070 | 0.73 | NR1H2 (0.65) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL13167610 | 0.73 | NR1H4 (0.51) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL18671898 | 0.70 | NR1H2 (0.61) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL14593303 | 0.70 | NR1H2 (0.61) | NR1H2NR1H3MLYCDHPGDSMN1; SMN2 | |
| SCHEMBL24901413 | 0.69 | NR1H2 (0.61) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL9621271 | 0.69 | NR1H2 (0.60) | NR1H2NR1H3MLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138879-A1 | COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1 | HYDRA BIOSCIENCES, INC. (US) | 2010-12-02 | — | — | WO | disclosed |