Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822708 | 0.77 | NR1H2 (0.45) | MAPTHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL13046004 | 0.74 | NR1H2 (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3819337 | 0.71 | KIF11 (0.45) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13167610 | 0.70 | NR1H4 (0.51) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL10890440 | 0.70 | NR1H2 (0.54) | ALDH1A1ALOX15MAPK1NR1H2NR1H3 | |
| SCHEMBL31125245 | 0.68 | MAPT (0.48) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL31125247 | 0.67 | MAPT (0.48) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL2823641 | 0.67 | RORC (0.43) | ALDH1A1MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL8924910 | 0.66 | NPC1 (0.53) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL18275111 | 0.66 | SRD5A2 (0.52) | ALDH1A1MEN1KMT2ATP53NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138879-A1 | COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1 | HYDRA BIOSCIENCES, INC. (US) | 2010-12-02 | — | — | WO | disclosed |