Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842161 | 0.78 | CHRM2 (0.67) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL296509 | 0.76 | MAPT (0.56) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL19373099 | 0.75 | APP (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9994731 | 0.74 | CHRM2 (0.50) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6894316 | 0.74 | CHRM2 (0.50) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7754741 | 0.74 | THRB (0.56) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4573527 | 0.74 | CHRM2 (0.50) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL14304332 | 0.74 | AGER (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL2776498 | 0.74 | IDO1 (0.56) | CHRM2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL11963390 | 0.74 | CHRM2 (0.50) | CHRM2MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507554-B2 | Quorum sensing antagonist and method of reducing a bacterial contamination using the quorum sensing antagonist | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2013-08-13 | — | — | US | disclosed |
| US-20100292261-A1 | QUORUM SENSING ANTAGONIST, METHOD OF PREVENTING A BIOFILM FORMATION USING THE QUORUM SENSING ANTAGONIST AND METHOD OF REDUCING A BACTERIAL CONTAMINATION USING THE QUORUM SENSING ANTAGONIST | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292261-A1 | QUORUM SENSING ANTAGONIST, METHOD OF PREVENTING A BIOFILM FORMATION USING THE QUORUM SENSING ANTAGONIST AND METHOD OF REDUCING A BACTERIAL CONTAMINATION USING THE QUORUM SENSING ANTAGONIST | BLVRB, PGLS, O60361 | CHRM2 3992/4885MEN1 4404/4885KMT2A 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.