Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998605 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL9624548 | 0.85 | ACHE (0.47) | NFE2L2CA1MAPTLMNAPOLB | |
| SCHEMBL4351525 | 0.85 | ACHE (0.47) | NFE2L2CA1CYP2A6LMNA | |
| SCHEMBL318785 | 0.82 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.82 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.82 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL318786 | 0.82 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.82 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL12692354 | 0.80 | ACHE (0.42) | CA1NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL13410607 | 0.80 | ACHE (0.42) | CA1NPC1RAB9AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100297016-A1 | QUARTERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2010-11-25 | — | — | US | disclosed |
| US-7732215-B2 | Cyanide sensing compounds and uses thereof | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2010-06-08 | — | — | US | disclosed |
| US-7718804-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080096281-A1 | Cyanide Sensing Compounds and Uses Thereof | GEDDES, CHRIS, DR. | 2008-04-24 | — | — | US | disclosed |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | GEDDES, CHRIS, DR. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297016-A1 | QUARTERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | NFE2L2 2313/4885RELA 394/4885PTGS1 3331/4885 |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | NFE2L2 2333/4885RELA 451/4885PTGS1 3825/4885 |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | SLC5A1, NISCH, SLC5A2 | NFE2L2 2333/4885RELA 451/4885PTGS1 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.