Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.74 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318785 | 1.00 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL318786 | 1.00 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 1.00 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 1.00 | NFE2L2 (0.74) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL700269 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL4585859 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL4585865 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL7164327 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL1239547 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 | |
| SCHEMBL4585867 | 0.88 | NFE2L2 (0.61) | NFE2L2RELAPTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013260-B1 | PROCESS FOR THE PREPARATION OF POLYESTERS CONTAINING 1,4-CYCLOHEXANEDIMETHANOL | EASTMAN CHEM CO (US) | 2016-04-06 | — | — | EP | claimed |
| US-4620055-A | Preparation of styrene and stilbene compounds | EASTMAN KODAK COMPANY (US) | 1986-10-28 | — | — | US | claimed |
| US-12312373-B2 | Cyclopropane skeleton monophosphine ligands, palladium complexes thereof, preparation methods and application | NANKAI UNIVERSITY (CN) | 2025-05-27 | — | — | US | disclosed |
| WO-2025063197-A1 | CRYSTAL, METHOD FOR PRODUCING CRYSTAL, AND METHOD FOR INDUCING SELF-ORGANIZATION OF SILANOL COMPOUND | 国立研究開発法人産業技術総合研究所 | 2025-03-27 | — | — | WO | disclosed |
| EP-4471039-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | Nankai University (CN) | 2024-12-04 | — | — | EP | disclosed |
| CN-114174312-B | Air-stable Ni (0) -olefin complexes and their use as catalysts or precatalysts | 科勒研究有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240376136-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGANDS, PALLADIUM COMPLEXES THEREOF, PREPARATION METHODS AND APPLICATION | EXTRAORDINARY SYNERGY TECHNOLOGY (TIANJIN) CO., LTD (CN) | 2024-11-14 | — | — | US | disclosed |
| CN-116693543-B | Calixarene-derived supermolecule macrocyclic host compound, preparation method and application thereof | 上海大学 | 2024-10-29 | — | — | CN | disclosed |
| US-12084538-B2 | Method for producing polymer | LG CHEM, LTD. (KR) | 2024-09-10 | — | — | US | disclosed |
| CN-116535439-B | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11798810-B2 | Resist underlayer film-forming composition containing amide solvent | NISSAN CHEMICAL CORPORATION (JP) | 2023-10-24 | — | — | US | disclosed |
| EP-0265373-B1 | PROCESS FOR CURING POLYISOCYANATE COATINGS | CIBA-GEIGY AG (CH) | 1991-03-13 | — | — | EP | disclosed |
| US-4861806-A | PHOTOPOLYMERIZATION, LATENCY | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4620055-A | Preparation of styrene and stilbene compounds | EASTMAN KODAK COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4533505-A | REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST | CIBA-GEIGY CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0062005-B1 | PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| EP-0062005-A1 | Process for the manufacture of styrene and/or stilbene derivatives | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |
| US-3946081-A | OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12312373-B2 | Cyclopropane skeleton monophosphine ligands, palladium complexes thereof, preparation methods and application | DDT, CPNE4, PIN1 | NFE2L2 1865/4885RELA 4057/4885PTGS1 2267/4885 |
| US-20240376136-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGANDS, PALLADIUM COMPLEXES THEREOF, PREPARATION METHODS AND APPLICATION | DDT, CPNE4, PIN1 | NFE2L2 1865/4885RELA 4057/4885PTGS1 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.