Sugi Predict

Sugi Predict / Compounds / SCHEMBL13052095

SCHEMBL13052095

SCHEMBL13052095

Oc1ccc(-c2cccc(-c3ccc(O)nn3)n2)nn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.43
▸ HPGD P15428 3/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ POLB P06746 1/20 0.43
▸ KDM4E B2RXH2 3/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ LMNA P02545 2/20 0.39
▸ TP53 P04637 2/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ HTT P42858 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ CCR1 P32246 2/20 0.39
▸ CCR8 P51685 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALPL P05186 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ ALPI P09923 1/20 0.39
▸ ALPG P10696 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13052126 0.76 KDM4E (0.75) ALDH1A1HPGDHSD17B10MAPTPOLB
SCHEMBL8515342 0.74 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10MAPTPOLB
SCHEMBL154932 0.72 — —
SCHEMBL29740320 0.72 — —
SCHEMBL16715989 0.71 CCR1 (0.76) ALDH1A1HPGDHSD17B10KDM4EL3MBTL1
SCHEMBL1456851 0.71 RAB9A (0.76) ALDH1A1HPGDHSD17B10MAPTPOLB
SCHEMBL3753156 0.71 CCR1 (0.76) ALDH1A1HPGDHSD17B10KDM4EL3MBTL1
SCHEMBL3744881 0.71 LMNA (0.43) ALDH1A1HPGDHSD17B10MAPTPOLB
SCHEMBL4653822 0.71 RAB9A (0.50) HPGDTP53SMN1; SMN2RAB9AMAPK1
SCHEMBL2015724 0.71 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10KDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034873-B2 Pyridazine and pyrrole compounds, processes for obtaining them and uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-05-19 — — US disclosed
US-9034873-B2 Pyridazine and pyrrole compounds, processes for obtaining them and uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-05-19 — — US disclosed
US-20100298562-A1 Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 — — US disclosed
US-20100298562-A1 Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 — — US disclosed
WO-2008012440-A2 PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2008-01-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298562-A1 Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses PPOX, PNPO, PLPBP ALDH1A1 1788/4885HPGD 482/4885HSD17B10 4488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.