Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160894 | 0.84 | NOS3 (0.50) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL4947766 | 0.84 | NOS3 (0.50) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL13013670 | 0.80 | CA2 (0.48) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL16930794 | 0.76 | PARP15 (0.46) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL1305251 | 0.76 | GSK3B (0.49) | NOS3NOS1GSK3BPOLBIDO1 | |
| SCHEMBL17396097 | 0.76 | CYP2D6 (0.62) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL322070 | 0.73 | PARP15 (0.78) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL15902206 | 0.73 | LMNA (0.52) | NOS3NOS1PARP15PARP10PARP2 | |
| SCHEMBL7532498 | 0.73 | CA2 (0.50) | NOS3NOS1PARP15PARP10PARP2 | |
| Hydrochloric Acid SCHEMBL5860266 | 0.71 | PRSS1 (0.54) | NOS3NOS1PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053573-B2 | Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-11-08 | — | — | US | disclosed |
| EP-1751122-B1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | disclosed |
| EP-1751122-A1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | Pierre Fabre Dermo-Cosmetique (FR) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005121108-A1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | POT1, TELO2, CLIC1 | NOS3 3186/4885NOS1 2285/4885PARP15 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.