SCHEMBL13054816

SCHEMBL13054816

COCOc1ccc(C2(c3ccc(OC)c(-c4ccccc4)c3)CCCCC2)cc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
C5AR1 P21730 2/20 0.38
PPARA Q07869 1/20 0.37
ITGA4 P13612 4/20 0.36
ITGB7 P26010 3/20 0.36
HDAC1 Q13547 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
CD274 Q9NZQ7 1/20 0.35
LMNA P02545 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PGR P06401 1/20 0.34
SYK P43405 1/20 0.34
ITGB1 P05556 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912709 0.81 C5AR1 (0.44) C5AR1PPARALMNAPTGDR2ALDH1A1
SCHEMBL12438743 0.80 BACE1 (0.43) MAOAMAOBPPARAITGA4ITGB7
SCHEMBL13054815 0.78 PPARA (0.49) PPARALMNAALDH1A1
SCHEMBL13054841 0.77 LMNA (0.38) PPARALMNAALDH1A1
SCHEMBL26299446 0.76 ALDH1A1 (0.43) C5AR1PPARAPTGDR2ALDH1A1
SCHEMBL13054808 0.73 PTGDR2 (0.44) LMNAPTGDR2
SCHEMBL12893200 0.73 LMNA (0.54) MAOAPPARAHDAC1LMNAALDH1A1
SCHEMBL8961826 0.73 MAOA (0.36) MAOAMAOBC5AR1PPARAPTGDR2
SCHEMBL13054818 0.73 PTGDR2 (0.45) EGFRMAOAMAOBPTGDR2SYK
SCHEMBL7461246 0.71 EGFR (0.49) EGFRPTGDR2SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 US disclosed
US-20130266343-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2013-10-10 US disclosed
US-20100291480-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO., LTD. (JP) 2010-11-18 US disclosed
US-7790342-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-07 US disclosed
US-20090226830-A1 Using in combination a p-terphenyl compound, N-N'-diphenyl-N,N'-di-p- tolyl-4,4''-diamino-p-terphenyl, as charge transport agent and a polycarbonate homo- and copolymer of bisphenol A or analogues as binder; providing an high photosensitive, improved residual potential and high durability HODOGAYA CHEMICAL CO., LTD. (JP) 2009-09-10 US disclosed