Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13054815 | 0.82 | PPARA (0.49) | LMNAPPARAESR1ESR2ALDH1A1 | |
| SCHEMBL12438744 | 0.77 | LMNA (0.46) | LMNAPPARAESR1ESR2ALDH1A1 | |
| SCHEMBL13054808 | 0.77 | PTGDR2 (0.44) | LMNASLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL13054816 | 0.77 | EGFR (0.39) | LMNAPPARAALDH1A1 | |
| SCHEMBL3954547 | 0.74 | LMNA (0.47) | LMNASLC6A4SLC6A3SLC6A2ALDH1A1 | |
| SCHEMBL14260413 | 0.73 | LMNA (0.52) | LMNAESR1ESR2SLC6A4SLC6A3 | |
| SCHEMBL19268516 | 0.71 | ESR1 (0.59) | LMNAPPARAESR1ESR2SLC6A4 | |
| SCHEMBL17523062 | 0.71 | ESR1 (0.59) | LMNAPPARAESR1ESR2SLC6A4 | |
| SCHEMBL25620272 | 0.71 | ESR1 (0.59) | LMNAPPARAESR1ESR2SLC6A4 | |
| SCHEMBL18892800 | 0.71 | PSMB1 (0.54) | LMNAESR1ESR2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808951-B2 | Electrophotographic photosensitive body | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20130266343-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | HODOGAYA CHEMICAL CO LTD (JP) | 2013-10-10 | — | — | US | disclosed |
| US-20100291480-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |