Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | CASP1 | P29466 | 5/20 | 0.57 |
| ▸ | CASP7 | P55210 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378873 | 0.89 | MEN1 (0.74) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL38663343 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL19248907 | 0.86 | CYP3A4 (0.75) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL1627835 | 0.83 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10516653 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10513549 | 0.83 | CYP3A4 (0.66) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10516343 | 0.83 | CYP3A4 (0.66) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10666102 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10672244 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL10516866 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100189653-A1 | Pyrone analogs for therapeutic treatment | LIMERICK BIOPHARMA, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | PC, PCK1, PYGL | ALDH1A1 3288/4885CYP3A4 2300/4885CYP2C9 3000/4885 |
| US-20100189653-A1 | Pyrone analogs for therapeutic treatment | PC, GLS2, CYP27A1 | ALDH1A1 1712/4885CYP3A4 718/4885CYP2C9 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.