Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | XDH | P47989 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119445 | 0.86 | MEN1 (0.60) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13056274 | 0.82 | BCL9 (0.66) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13056303 | 0.82 | CYP1A2 (0.64) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL5133662 | 0.79 | NOX4 (0.73) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL118852 | 0.78 | ABCB1 (0.56) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13076079 | 0.78 | BCL9 (0.61) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL19749977 | 0.75 | ABCB1 (0.61) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13056268 | 0.74 | MAPT (0.66) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13056272 | 0.73 | BCL9 (0.67) | ABCB1MEN1KMT2ACYP1A1CYP1A2 | |
| Galangin SCHEMBL29393121 | 0.72 | MEN1 (1.00) | ABCB1MEN1KMT2ACYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | PC, PCK1, PYGL | ABCB1 1417/4885MEN1 2302/4885KMT2A 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.