Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 9/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692818 | 0.57 | KMT2A (0.61) | MAPK1PTPN1HTTRAB9ALMNA | |
| SCHEMBL3425439 | 0.56 | CCR5 (0.53) | CCR5MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL987942 | 0.56 | EPHX1 (0.46) | PTPN1GLAHPGDRECQLMAPT | |
| SCHEMBL9292528 | 0.55 | NPC1 (0.53) | MAPK1GLAHPGDRECQLKDM4E | |
| SCHEMBL3726123 | 0.55 | SMN1; SMN2 (0.60) | MAPK1GLAHPGDRECQLMAPT | |
| SCHEMBL3428926 | 0.54 | HTR2A (0.61) | MAPK1CCR5KDM4EHTTLMNA | |
| SCHEMBL21739939 | 0.54 | HTR2A (0.61) | MAPK1CCR5KDM4EHTTLMNA | |
| SCHEMBL21739938 | 0.54 | HTR2A (0.61) | MAPK1CCR5KDM4EHTTLMNA | |
| Phosphoric Acid SCHEMBL9105394 | 0.54 | LMNA (0.50) | CCR5LMNA | |
| SCHEMBL10257963 | 0.54 | LTA4H (0.50) | PTPN1CCR5LMNACYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | MAPK1 2749/4885PTPN1 2433/4885GLA 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.