SCHEMBL13061369

SCHEMBL13061369

CCCc1ccc(N2CCOCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.52
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
HTT P42858 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALOX15 P16050 2/20 0.52
MAPK1 P28482 2/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
RAB9A P51151 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
NPC1 O15118 2/20 0.51
GAA P10253 2/20 0.51
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
ATM Q13315 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18405980 0.90 L3MBTL1 (0.44) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL3399680 0.89 LMNA (0.52) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL19245042 0.86 S1PR1 (0.59) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL27249154 0.84 CHKA (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL178277 0.84 MAPT (0.60) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL8349588 0.84 CHKA (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL13061371 0.82 CHKA (0.53) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL16003056 0.82 MAPT (0.58) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL8189516 0.81 AGXT (0.61) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL25291736 0.81 LMNA (0.64) MAPTALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446977-A Blue-sensitive resin combination, the colour filter and image display device manufactured using the composition DONGWOO FINE CHEM CO LTD 2019-11-12 CN claimed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 EP disclosed
US-20200354408-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2020-11-12 US disclosed
US-20200231596-A1 MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE CANGET BIOTEKPHARMA 2020-07-23 US disclosed
CN-110446977-A Blue-sensitive resin combination, the colour filter and image display device manufactured using the composition DONGWOO FINE CHEM CO LTD 2019-11-12 CN disclosed
CN-104298074-B Transparent pixels are formed with photosensitive polymer combination and the colour filter formed using it TONGWOO FINE CHEMICALS CO., LTD. (KR) 2019-11-01 CN disclosed
CN-105446077-B Photosensitive polymer combination 东友精细化工有限公司 2019-10-25 CN disclosed
US-10392392-B2 Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors TOLERO PHARMACEUTICALS, INC. (US) 2019-08-27 US disclosed
CN-110121679-A Blue photosensitive resin composition, color filter and image display device manufactured by using the same 东友精细化工有限公司 2019-08-13 CN disclosed
CN-110023838-A Self-luminous photosensitive polymer combination, the colour filter and image display device manufactured using it 东友精细化工有限公司 2019-07-16 CN disclosed
CN-105431752-B Phase difference film and the image display device for having the phase difference film 东友精细化工有限公司 2018-12-25 CN disclosed
US-9802904-B2 Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2017-10-31 US disclosed
EP-2938344-B1 PIPERAZINE-SUBSTITUTED [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES MERCK SHARP & DOHME (US) 2017-06-21 EP disclosed
CN-106842816-A Self-luminous Photosensitve resin composition, the colored filter and image display device that are manufactured with it 东友精细化工有限公司 2017-06-13 CN disclosed
CN-105911820-A SELF EMISSION TYPE PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER MANUFACTURED USING THEREOF AND IMAGE DISPLAY DEVICE HAVING THE SAME 东友精细化工有限公司 2016-08-31 CN disclosed
US-20120165309-A1 HETERO RING DERIVATIVE ASTELLAS PHARMA INC. (JP) 2012-06-28 US disclosed
CN-102385252-A Dyeing photosensitive resin combination, colorful color filter and liquid crystal display apparatus with colorful color filter DONG WOO FINE CHEMICAL CO LTD 2012-03-21 CN disclosed
US-20100324009-A1 Substituted Sulfonamide Compounds GRUENENTHAL GMBH (DE) 2010-12-23 US disclosed
US-20100317644-A1 Substituted Sulfonamide Compounds GRUENENTHAL GMBH (DE) 2010-12-16 US disclosed
US-20080153843-A1 SUBSTITUTED SULFONAMIDE COMPOUNDS GRUENENTHAL GMBH (DE) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231596-A1 MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE TP53, BRCA1, MET MAPT 1334/4885ALDH1A1 4214/4885MEN1 1206/4885
US-20100317644-A1 Substituted Sulfonamide Compounds SULT2A1, STS, SULT1A1 MAPT 2195/4885ALDH1A1 1535/4885MEN1 4354/4885
US-20100324009-A1 Substituted Sulfonamide Compounds SULT2A1, STS, SULT1A1 MAPT 2195/4885ALDH1A1 1535/4885MEN1 4354/4885
US-20080153843-A1 SUBSTITUTED SULFONAMIDE COMPOUNDS SULT2A1, STS, SULT1A1 MAPT 2195/4885ALDH1A1 1535/4885MEN1 4354/4885
US-20120165309-A1 HETERO RING DERIVATIVE IL2, PIK3R2, IL2RA MAPT 3968/4885ALDH1A1 3496/4885MEN1 4630/4885
US-10392392-B2 Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors PIM1, PIM2, PIM3 MAPT 727/4885ALDH1A1 3557/4885MEN1 2155/4885
US-20200354408-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP MAPT 4110/4885ALDH1A1 3037/4885MEN1 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.