⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838404 | 0.86 | RAB9A (0.38) | — | |
| SCHEMBL13016503 | 0.81 | APOBEC3A (0.33) | — | |
| SCHEMBL13062708 | 0.78 | HTR6 (0.31) | — | |
| SCHEMBL1842471 | 0.77 | HTR2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL1231715 | 0.76 | HTR2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL1842432 | 0.76 | HTR2A (0.32) | — | |
| SCHEMBL12659353 | 0.75 | CCNA2 (0.30) | — | |
| SCHEMBL5146698 | 0.68 | MBOAT4 (0.32) | — | |
| SCHEMBL1842474 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL1839924 | 0.67 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |