Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230752 | 0.87 | DRD2 (0.64) | DRD2HTR2CHTR2BCHRM2HTR1A | |
| SCHEMBL11393853 | 0.85 | DRD2 (0.59) | DRD2HTR2CDRD3 | |
| Hydrochloric Acid SCHEMBL11397089 | 0.84 | DRD2 (0.58) | DRD2HTR2CDRD3 | |
| SCHEMBL6926283 | 0.83 | DRD2 (0.72) | DRD2HTR2CHTR2BCHRM2HTR1A | |
| SCHEMBL13018937 | 0.82 | DRD3 (0.61) | DRD2HTR2CHTR2BCHRM2HTR1A | |
| SCHEMBL14221731 | 0.80 | HTR2C (0.50) | DRD2HTR2CHTR2BCHRM2HTR1A | |
| SCHEMBL1065758 | 0.80 | HTR2C (0.77) | DRD2HTR2CHTR2BHTR1AKDM1A | |
| SCHEMBL29728437 | 0.79 | BRD4 (0.60) | DRD2HTR2CGRM2 | |
| SCHEMBL16799733 | 0.79 | BRD4 (0.60) | DRD2HTR2CGRM2 | |
| SCHEMBL25636100 | 0.79 | DRD2 (0.51) | DRD2HTR2CHTR2BCHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CYTOPATHFINDER, INC. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CCR2, CCR1, CCR5 | DRD2 1453/4885HTR2C 509/4885HTR2B 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.