Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018940 | 0.84 | CYP17A1 (0.49) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL8789168 | 0.84 | CYP17A1 (0.51) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL9265494 | 0.84 | CYP17A1 (0.54) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL8787300 | 0.83 | CYP17A1 (0.51) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL13063691 | 0.80 | CYP17A1 (0.46) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL8670858 | 0.79 | CYP17A1 (0.47) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL23143320 | 0.77 | ADRB1 (0.49) | CYP17A1ADRB1NPSR1FFAR4HRH3 | |
| SCHEMBL8661026 | 0.76 | CNR1 (0.45) | CYP17A1ADRB1FFAR4HRH3MAPT | |
| SCHEMBL9023401 | 0.75 | HTR7 (0.48) | ADRB1FFAR4HRH3CXCR3MAPT | |
| SCHEMBL13063400 | 0.75 | CYP17A1 (0.56) | CYP17A1ADRB1NPSR1FFAR4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CYTOPATHFINDER, INC. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CCR2, CCR1, CCR5 | CYP17A1 3706/4885ADRB1 291/4885NPSR1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.