SCHEMBL13063433

SCHEMBL13063433

CCC1CCC(C(F)(F)F)(C(F)(F)F)CC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449597 0.82
SCHEMBL21758971 0.80
SCHEMBL25636487 0.79 KDM4E (0.37) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL23177943 0.77 KDM4E (0.36) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL24767081 0.77 KDM4E (0.36) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL18377811 0.74 KDM4E (0.34) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL19449595 0.73
SCHEMBL178339 0.72 KDM4E (0.42) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL18236376 0.72
SCHEMBL22747702 0.71 KDM4E (0.41) KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230276694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-31 US disclosed
US-11718634-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
EP-4206210-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-05 EP disclosed
US-11678563-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-13 US disclosed
US-11678563-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-13 US disclosed
EP-4122941-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-01-25 EP disclosed
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
EP-3231809-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-06-08 EP disclosed
US-11056658-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-07-06 US disclosed
US-20200075870-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-05 US disclosed
EP-3613751-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-02-26 EP disclosed
US-10236456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-19 US disclosed
EP-3231809-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-10-18 EP disclosed
US-20170294597-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-10-12 US disclosed
US-20170294597-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-10-12 US disclosed
US-20100331243-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331243-A1 ORGANIC COMPOUNDS AND THEIR USES OAT, OTC, AOX1 KDM4E 4021/4885ALDH1A1 135/4885GAA 283/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885ALDH1A1 128/4885GAA 1387/4885
US-11056658-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885ALDH1A1 128/4885GAA 1387/4885
US-11678563-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885ALDH1A1 128/4885GAA 1387/4885
US-20200075870-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4410/4885ALDH1A1 96/4885GAA 941/4885
US-10236456-B2 Organic electroluminescent materials and devices ADORA1, ADORA3, M6PR KDM4E 2596/4885ALDH1A1 1605/4885GAA 3610/4885
US-20230276694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885ALDH1A1 128/4885GAA 1387/4885
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDM4E 1104/4885ALDH1A1 1245/4885GAA 3612/4885
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, KCNH3, KCNH2 KDM4E 1186/4885ALDH1A1 1237/4885GAA 3518/4885
US-11718634-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG KDM4E 1123/4885ALDH1A1 1386/4885GAA 3689/4885
US-20170294597-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ADORA1, ADORA3, M6PR KDM4E 2596/4885ALDH1A1 1605/4885GAA 3610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.