Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063542 | 0.93 | SRC (0.36) | SRCMAPTBRAFRAD52NCOA3 | |
| SCHEMBL13063827 | 0.91 | LMNA (0.39) | SRCCCR4ALDH1A1 | |
| SCHEMBL3806994 | 0.89 | MAP2K1 (0.42) | — | |
| SCHEMBL13063540 | 0.89 | SRC (0.37) | SRCMAPTCCR4 | |
| SCHEMBL3809160 | 0.86 | LRRK2 (0.35) | SRCCCR4 | |
| SCHEMBL13063853 | 0.85 | SRC (0.38) | SRCMAPTRAD52CCR4ALDH1A1 | |
| SCHEMBL13063846 | 0.83 | MAP2K1 (0.41) | — | |
| SCHEMBL3804823 | 0.82 | ADRA2A (0.36) | SRCBRAFCCR4 | |
| SCHEMBL13063861 | 0.82 | MAP2K1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL3804582 | 0.80 | MAP2K1 (0.42) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010145197-A1 | NOVEL 6-ARYLAMINO PYRIDONE SULFONAMIDES AND 6-ARYLAMINO PYRAZINONE SULFONAMDIES AS MEK INHIBITORS | CHEMIZON (BEIJING), LTD. (CN) | 2010-12-23 | — | — | WO | disclosed |