SCHEMBL1306455

SCHEMBL1306455

O=P(O)(O)n1c(=S)oc2ccc(-c3ccccc3)c(-c3ccccc3)c21

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 2/20 0.34
CDC14A Q9UNH5 2/20 0.34
MAOB P27338 1/20 0.31
POLB P06746 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CTRC Q99895 2/20 0.30
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ATM Q13315 1/20 0.30
PLEC Q15149 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8081468 0.81 CDC14B (0.33) CDC14BCDC14AMAOBKMT2AALDH1A1
SCHEMBL7857381 0.75 KMT2A (0.33) MAOBPOLBCTRCKMT2AMEN1
SCHEMBL3371626 0.69 ALDH1A1 (0.45) POLBKMT2AMEN1USP2ALDH1A1
Phosphoric Acid SCHEMBL27982532 0.69 HDAC4 (0.45) ALDH1A1GPR84
Phosphoric Acid SCHEMBL242261 0.64 HNF4A (0.48) ALDH1A1GPR84
Phosphoric Acid SCHEMBL28476358 0.62 BACE1 (0.45) KMT2AMEN1ALDH1A1GPR84
SCHEMBL608536 0.60 ALDH1A1 (0.50) CTRCALDH1A1
SCHEMBL3360427 0.60 KDM4E (0.40) CDC14BCDC14APOLBKDM4EALDH1A1
Phosphoric Acid SCHEMBL28543871 0.60 TDP2 (0.42) ALDH1A1GPR84
Phosphoric Acid SCHEMBL641209 0.60 WDR5 (0.46) KDM4EKMT2AMEN1ALDH1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053151-B2 Phosphonate containing photoconductors XEROX CORPORATION (US) 2011-11-08 US claimed
US-20090297967-A1 PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-03 US claimed
US-5834581-A Process for making polyimide-polyamic ester copolymers OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-11-10 US claimed
EP-4600355-A1 NUCLEIC ACID EXTRACTION METHOD, NUCLEIC ACID AMPLIFICATION METHOD, NUCLEIC ACID EXTRACTION KIT, AND PCR TEST KIT National Institute for Materials Science (JP) 2025-08-13 EP disclosed
US-20240045329-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELECTRONIC COMPONENT, ANTENNA ELEMENT, SEMICONDUCTOR PACKAGE, AND COMPOUND TORAY INDUSTRIES, INC. (JP) 2024-02-08 US disclosed
US-10023530-B2 Diamine, polyamic acid, and polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-07-17 US disclosed
US-9976086-B2 Liquid crystal aligning agent containing polyimide precursor having thermally-leaving group and/or polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed
US-20160264520-A1 NOVEL DIAMINE, POLYAMIC ACID, AND POLYIMIDE NISSAN CHEMICAL INDUSTRIES. LTD. (JP) 2016-09-15 US disclosed
US-20160264867-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING POLYIMIDE PRECURSOR HAVING THERMALLY-LEAVING GROUP AND/OR POLYIMIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
US-9284393-B2 Biomolecule-compatible, highly branched polymer and biomolecular-recognition surface KYUSHU UNIVERSITY (JP) 2016-03-15 US disclosed
US-8062816-B2 Phosphonate hole blocking layer photoconductors XEROX CORPORATION (US) 2011-11-22 US disclosed
US-20090297967-A1 PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-03 US disclosed
US-5834581-A Process for making polyimide-polyamic ester copolymers OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-11-10 US disclosed
US-5789525-A Process for making polyimides from diamines and tetracarboxylic diacid diester OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023530-B2 Diamine, polyamic acid, and polyimide H1-2, H1-4, H1-0 CDC14B 3061/4885CDC14A 3022/4885MAOB 622/4885
US-20160264520-A1 NOVEL DIAMINE, POLYAMIC ACID, AND POLYIMIDE H1-4, H1-2, H1-5 CDC14B 2945/4885CDC14A 3039/4885MAOB 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.