Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065638 | 0.81 | SLC5A2 (0.56) | ALDH1A1HTTSLC5A2LMNA | |
| SCHEMBL13065336 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HTTP2RY2P2RY4MEN1 | |
| SCHEMBL441997 | 0.79 | LMNA (0.66) | ALDH1A1HTTP2RY6NT5EP2RY14 | |
| SCHEMBL13678671 | 0.79 | LMNA (0.66) | ALDH1A1HTTP2RY6NT5EP2RY14 | |
| Hydrochloric Acid SCHEMBL11852550 | 0.78 | LMNA (0.65) | ALDH1A1HTTP2RY6NT5EP2RY14 | |
| SCHEMBL2984401 | 0.78 | SLC28A1 (0.63) | P2RY6P2RY14P2RY2P2RY4 | |
| SCHEMBL2984399 | 0.78 | SLC28A1 (0.63) | P2RY6P2RY14P2RY2P2RY4 | |
| SCHEMBL13065492 | 0.77 | MEN1 (0.56) | ALDH1A1HTTP2RY2MEN1USP2 | |
| SCHEMBL6273371 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAPOLBKMT2A | |
| SCHEMBL6273372 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279974-A1 | Nucleosides With Non-Natural Bases as Anti-Viral Agents | IDENIX PHARMACEUTICALS, INC. | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279974-A1 | Nucleosides With Non-Natural Bases as Anti-Viral Agents | PNP, NSUN2, NME2 | ALDH1A1 3538/4885HTT 2145/4885P2RY6 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.