SCHEMBL1306565

SCHEMBL1306565

OC[C@H](O)c1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 7/20 0.42
HMOX1 P09601 1/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC18A3 Q16572 2/20 0.40
HTR2A P28223 1/20 0.40
CXCR3 P49682 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP1A2 P05177 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
HTR3A P46098 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237732 1.00 IGF1R (0.42) IGF1RHMOX1CYP3A4TSHRMEN1
SCHEMBL1305581 1.00 IGF1R (0.42) IGF1RHMOX1CYP3A4TSHRMEN1
SCHEMBL17438169 0.87 TSHR (0.48) CYP3A4TSHRHTR3A
SCHEMBL2368070 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL1986354 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL241160 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL16070705 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL16070654 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL3175979 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL3839205 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) 2025-02-27 US disclosed
EP-4491270-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES The University of Hong Kong (HK) 2025-01-15 EP disclosed
CN-119306769-A Iron complexes for enantioselective cis dihydroxylation of olefins 香港大学 2025-01-14 CN disclosed
CN-114560892-A Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof 广东工业大学 2022-05-31 CN disclosed
EP-3192503-B1 NOVEL PHARMACEUTICAL COMPOSITION CONTAINING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF FUJIFILM TOYAMA CHEMICAL CO LTD (JP) 2019-08-14 EP disclosed
EP-2975022-B1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF FUJIFILM TOYAMA CHEMICAL CO LTD (JP) 2019-05-08 EP disclosed
US-20190054179-A1 NOVEL PHARMACEUTICAL COMPOSITION CONTAINING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2019-02-21 US disclosed
US-10149911-B2 Pharmaceutical composition containing hydroxamic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2018-12-11 US disclosed
US-10123990-B2 Method for using novel hydroxamic acid derivative and antibacterial substance in combination TOYAMA CHEMICAL CO., LTD. (JP) 2018-11-13 US disclosed
US-9862676-B2 Hydroxamic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-8053426-B2 Such as 11-beta-[4-(1,2-Dihydroxyethyl)phenyl]-20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17 alpha-pregna-4,9-dien-3-one or corresponding 4-(hydroxyacetyl)phenyl derivative thereof; endometriosis, myomas or hormone-dependent tumors, such as breast cancer BAYER SCHERING PHARMA AG (DE) 2011-11-08 US disclosed
US-20100113488-A1 MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY 2010-05-06 US disclosed
US-20100113488-A1 MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY 2010-05-06 US disclosed
EP-2081951-B1 PROGESTERONE RECEPTOR ANTAGONISTS BAYER SCHERING PHARMA AG (DE) 2010-04-21 EP disclosed
EP-2081951-B1 PROGESTERONE RECEPTOR ANTAGONISTS BAYER SCHERING PHARMA AG (DE) 2010-04-21 EP disclosed
US-20080200440-A1 Progesterone receptor antagonists BAYER INTELLECTUAL PROPERTY GMBH (DE) 2008-08-21 US disclosed
US-20080200440-A1 Progesterone receptor antagonists BAYER INTELLECTUAL PROPERTY GMBH (DE) 2008-08-21 US disclosed
US-20080200440-A1 Progesterone receptor antagonists BAYER INTELLECTUAL PROPERTY GMBH (DE) 2008-08-21 US disclosed
WO-2008079836-A2 MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-07-03 WO disclosed
WO-2008058767-A1 PROGESTERONE RECEPTOR ANTAGONISTS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10149911-B2 Pharmaceutical composition containing hydroxamic acid derivative or salt thereof H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, EGLN2, HAAO IGF1R 4702/4885HMOX1 476/4885CYP3A4 2841/4885
US-20080200440-A1 Progesterone receptor antagonists PGR, PGRMC2, GNRHR IGF1R 405/4885HMOX1 2976/4885CYP3A4 469/4885
US-20100113488-A1 MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS F12, F7, F5 IGF1R 1985/4885HMOX1 3323/4885CYP3A4 343/4885
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES SQLE, NFE2L2, FECH IGF1R 4549/4885HMOX1 7/4885CYP3A4 127/4885
US-20190054179-A1 NOVEL PHARMACEUTICAL COMPOSITION CONTAINING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF HAAO, HPD, HCAR2 IGF1R 4027/4885HMOX1 94/4885CYP3A4 2793/4885
US-10123990-B2 Method for using novel hydroxamic acid derivative and antibacterial substance in combination EGLN2, NGLY1, NAAA IGF1R 3989/4885HMOX1 305/4885CYP3A4 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.