SCHEMBL237732

SCHEMBL237732

OCC(O)c1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 7/20 0.42
HMOX1 P09601 1/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC18A3 Q16572 2/20 0.40
HTR2A P28223 1/20 0.40
CXCR3 P49682 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP1A2 P05177 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
HTR3A P46098 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1306565 1.00 IGF1R (0.42) IGF1RHMOX1CYP3A4TSHRMEN1
SCHEMBL1305581 1.00 IGF1R (0.42) IGF1RHMOX1CYP3A4TSHRMEN1
SCHEMBL17438169 0.87 TSHR (0.48) CYP3A4TSHRHTR3A
SCHEMBL2368070 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL1986354 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL241160 0.82 IGF1R (0.43) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL16070705 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL16070654 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL3175979 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3
SCHEMBL3839205 0.81 IGF1R (0.40) IGF1RHMOX1MEN1KMT2ASLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292417-A Process for producing carboxylic acid 赣南医学院 2021-08-24 CN claimed
CN-111171085-A Rhamnose donor protected by orthocarbonate, and preparation method and application thereof 山东大学 2020-05-19 CN claimed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
CN-121586713-A Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases 百济神州(苏州)生物科技有限公司 2026-02-27 CN disclosed
CN-118340754-B Compound for treating heart failure and related diseases and application thereof 源道医药(苏州)有限公司 2025-03-11 CN disclosed
CN-119490387-A Compounds for the treatment of pain-related diseases 源道医药(苏州)有限公司 2025-02-21 CN disclosed
WO-2025021217-A1 QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE BEIGENE SWITZERLAND GMBH (CH) 2025-01-30 WO disclosed
CN-118340754-A Compound for treating heart failure and related diseases and application thereof 源道医药(苏州)有限公司 2024-07-16 CN disclosed
US-20240166609-A1 ANTIBACTERIAL COMPOUNDS BLACKSMITH MEDICINES, INC. 2024-05-23 US disclosed
WO-2024082872-A1 PAK4 KINASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 成都海博为药业有限公司 2024-04-25 WO disclosed
CN-112638985-B Fluorine-containing aromatic polymer and method for producing same 大金工业株式会社 2024-03-15 CN disclosed
US-20030176528-A1 Photosensitive resin composition, dry film, and workpiece using the same MITSUI CHEMICALS, INC. (JP) 2003-09-18 US disclosed
US-20030032806-A1 Oxidation of carbon-boron bonds CAI WEILING (US) 2003-02-13 US disclosed
US-20020169206-A1 Substituted biphenyl compounds for the treatment of inflammation G.D. SEARLE & CO. (US) 2002-11-14 US disclosed
US-20020049352-A1 Oxidation of carbon-boron bonds CAI WEILING (US) 2002-04-25 US disclosed
EP-1167329-A2 Oxidation of carbon-boron bonds Pfizer Products Inc. (US) 2002-01-02 EP disclosed
EP-0794942-B1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION SEARLE & CO (US) 2000-05-31 EP disclosed
US-6043235-A 11β-aryl-17, 17-spirothiolane-substituted steroids RESEARCH TRIANGLE INSTITUTE (US) 2000-03-28 US disclosed
EP-0794942-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-09-17 EP disclosed
WO-1996016934-A1 SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169206-A1 Substituted biphenyl compounds for the treatment of inflammation AHR, ARNT, GPBAR1 IGF1R 1701/4885HMOX1 47/4885CYP3A4 206/4885
US-20240166609-A1 ANTIBACTERIAL COMPOUNDS MRPL21, MPO, RPN2 IGF1R 4070/4885HMOX1 365/4885CYP3A4 3548/4885
US-20030032806-A1 Oxidation of carbon-boron bonds CYBB, FOSB, SCO2 IGF1R 2935/4885HMOX1 128/4885CYP3A4 989/4885
US-20020049352-A1 Oxidation of carbon-boron bonds CYBB, FOSB, SCO2 IGF1R 2935/4885HMOX1 128/4885CYP3A4 989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.