Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065731 | 0.89 | DHODH (0.47) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065738 | 0.87 | HPGD (0.42) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065745 | 0.86 | ABCG2 (0.39) | DHODHMEN1KMT2AATMLMNA | |
| SCHEMBL13065732 | 0.86 | MAPK14 (0.45) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065735 | 0.86 | LMNA (0.48) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065585 | 0.84 | SLC16A3 (0.38) | DHODHMAPTCYP3A4ALOX15CYP19A1 | |
| SCHEMBL13065740 | 0.83 | LMNA (0.39) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065729 | 0.83 | KDM4E (0.51) | DHODHMEN1KMT2AATMLMNA | |
| SCHEMBL16784744 | 0.83 | PDE10A (0.40) | DHODHMEN1KMT2ALMNAPDE10A | |
| SCHEMBL13065599 | 0.81 | MEN1 (0.41) | MEN1KMT2AATMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | DHODH 3278/4885MEN1 3364/4885KMT2A 4381/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | DHODH 3278/4885MEN1 3364/4885KMT2A 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.