Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065744 | 0.90 | ABCG2 (0.48) | ABCG2MAPTCYP3A4SMN1; SMN2DHODH | |
| SCHEMBL13065730 | 0.88 | ABCG2 (0.50) | ABCG2MAPTCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL13065739 | 0.88 | ALDH1A1 (0.44) | ABCG2MAPTSMN1; SMN2DHODHABCB1 | |
| SCHEMBL13065736 | 0.88 | BCL9 (0.44) | ABCG2MAPTCYP3A4SMN1; SMN2DHODH | |
| SCHEMBL13065741 | 0.87 | DHODH (0.47) | ABCG2MAPTCYP3A4SMN1; SMN2DHODH | |
| SCHEMBL13065737 | 0.86 | DHODH (0.39) | MAPTCYP3A4SMN1; SMN2ALOX15DHODH | |
| SCHEMBL13065612 | 0.86 | CNR1 (0.36) | MAPTCYP3A4CNR1CNR2SMN1; SMN2 | |
| SCHEMBL13065734 | 0.85 | SMN1; SMN2 (0.40) | ABCG2MAPTSMN1; SMN2DHODHABCB1 | |
| SCHEMBL13065743 | 0.85 | KDM4E (0.40) | ABCG2MAPTSMN1; SMN2DHODHABCB1 | |
| SCHEMBL13065608 | 0.83 | MEN1 (0.39) | MAPTCYP3A4CNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | ABCG2 1063/4885MAPT 3092/4885CYP3A4 4203/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | ABCG2 1063/4885MAPT 3092/4885CYP3A4 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.