Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307077 | 0.93 | SLC2A1 (0.42) | SCN1ASCN2ASCN3ASLC2A1CYP2D6 | |
| SCHEMBL1307083 | 0.93 | SLC2A1 (0.42) | SCN1ASCN2ASCN3ASLC2A1CYP2D6 | |
| SCHEMBL1306574 | 0.88 | TDP1 (0.46) | HSD17B10MAPTKDM4E | |
| SCHEMBL1306652 | 0.87 | LMNA (0.43) | SCN1ASCN2ASCN3ASLC2A1CYP2D6 | |
| SCHEMBL1306254 | 0.86 | P2RX3 (0.60) | SLC2A1CYP2D6CYP2C19HSD17B10P2RX3 | |
| SCHEMBL1306250 | 0.86 | P2RX3 (0.60) | SLC2A1CYP2D6CYP2C19HSD17B10P2RX3 | |
| SCHEMBL1306488 | 0.83 | L3MBTL1 (0.48) | CYP2C19CYP1A2TSHRHSD17B10LMNA | |
| SCHEMBL1305476 | 0.83 | MAPT (0.49) | CYP2D6CYP2C9TSHRLMNAMAPT | |
| SCHEMBL1305646 | 0.83 | LMNA (0.42) | SLC2A1CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1305641 | 0.83 | LMNA (0.42) | SLC2A1CYP2D6CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |