Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068728 | 1.00 | GRM5 (0.35) | GRM5BTKEGFRERBB2KDR | |
| SCHEMBL13846647 | 0.89 | — | — | |
| SCHEMBL13068671 | 0.88 | GRM5 (0.36) | GRM5EGFRERBB2KDR | |
| SCHEMBL13846777 | 0.86 | ALDH1A1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL13069050 | 0.85 | SPR (0.34) | KDM4EALDH1A1POLBHPGDCALCRL | |
| SCHEMBL13068721 | 0.84 | NAMPT (0.31) | POLB | |
| SCHEMBL13069055 | 0.83 | ALOX15 (0.37) | ALDH1A1POLBCALCRL | |
| SCHEMBL13068974 | 0.82 | CALCRL (0.33) | KDM4EALDH1A1HSD17B10CALCRL | |
| SCHEMBL13846735 | 0.81 | MMP13 (0.41) | BTKEGFRKDM4EALDH1A1POLB | |
| SCHEMBL13068575 | 0.80 | ADM2 (0.32) | EGFRHPGDCALCRLKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251339-A2 | COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |