Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | PHGDH | O43175 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069540 | 0.85 | ALDH1A1 (0.51) | L3MBTL1NPC1RAB9AALDH1A1MGLL | |
| SCHEMBL11789535 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL24528365 | 0.83 | RAB9A (0.53) | L3MBTL1NPC1RAB9AALDH1A1PHGDH | |
| SCHEMBL11789537 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL13165368 | 0.83 | RAB9A (0.53) | L3MBTL1NPC1RAB9AALDH1A1PHGDH | |
| SCHEMBL11788530 | 0.78 | AKR1C3 (0.55) | L3MBTL1ALDH1A1AKR1C3 | |
| SCHEMBL11788058 | 0.77 | MAPT (0.54) | L3MBTL1ALDH1A1PHGDHMGLLHPGD | |
| SCHEMBL10008020 | 0.76 | NPC1 (0.54) | L3MBTL1NPC1RAB9AALDH1A1PHGDH | |
| SCHEMBL10008021 | 0.76 | NPC1 (0.54) | L3MBTL1NPC1RAB9AALDH1A1PHGDH | |
| SCHEMBL10458323 | 0.71 | RAB9A (1.00) | L3MBTL1NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1775290-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-7795258-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7795258-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1775290-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | CYP4Z1, PNPO, PLPBP | L3MBTL1 2906/4885NPC1 1625/4885RAB9A 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.