Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069050 | 0.85 | SPR (0.34) | — | |
| SCHEMBL13068721 | 0.83 | NAMPT (0.31) | PLK1NAMPT | |
| SCHEMBL3042197 | 0.81 | CALCRL (0.44) | — | |
| SCHEMBL550430 | 0.81 | CALCRL (0.44) | — | |
| SCHEMBL550234 | 0.81 | CALCRL (0.44) | — | |
| SCHEMBL13846777 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL10253041 | 0.80 | EIF2AK3 (0.34) | EIF2AK3NOTUMHTR2CHTR2BBTK | |
| SCHEMBL13068728 | 0.77 | GRM5 (0.35) | BTKEGFR | |
| SCHEMBL13068645 | 0.77 | GRM5 (0.35) | BTKEGFR | |
| SCHEMBL13068979 | 0.77 | MMP13 (0.41) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251339-A2 | COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |