Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742780 | 0.84 | OPRL1 (0.53) | MEN1KMT2AOPRL1NPY5RTGM2 | |
| SCHEMBL13078162 | 0.82 | PKM (0.47) | MEN1KMT2AOPRL1TSHRSMN1; SMN2 | |
| SCHEMBL3742290 | 0.81 | OPRL1 (0.69) | OPRL1OPRM1OPRK1 | |
| SCHEMBL16812348 | 0.78 | OPRL1 (0.48) | OPRL1SMN1; SMN2OPRM1OPRK1C5AR1 | |
| SCHEMBL13077798 | 0.77 | KMT2A (0.54) | MEN1KMT2AOPRL1TSHRMAPT | |
| SCHEMBL13078099 | 0.75 | AOC2 (0.37) | MEN1KMT2AOPRL1SMN1; SMN2OPRM1 | |
| SCHEMBL13078159 | 0.74 | L3MBTL1 (0.38) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL12362459 | 0.73 | OPRL1 (0.44) | MEN1KMT2AOPRL1OPRM1OPRK1 | |
| SCHEMBL12362425 | 0.72 | OPRL1 (0.43) | OPRL1OPRM1OPRK1C5AR1 | |
| SCHEMBL12362454 | 0.72 | L3MBTL1 (0.46) | MEN1KMT2AOPRL1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | MEN1 4821/4885KMT2A 4361/4885OPRL1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.