Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3733538 | 0.85 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL13078162 | 0.80 | PKM (0.47) | AOC2OPRL1LMNASMN1; SMN2MEN1 | |
| SCHEMBL13078159 | 0.77 | L3MBTL1 (0.38) | AOC2CA1CA2CA9OXTR | |
| SCHEMBL13078098 | 0.75 | MEN1 (0.48) | OPRL1OPRM1OPRK1C5AR1SMN1; SMN2 | |
| SCHEMBL16812348 | 0.73 | OPRL1 (0.48) | AOC2OPRL1OPRM1OPRK1C5AR1 | |
| SCHEMBL13077798 | 0.72 | KMT2A (0.54) | OPRL1LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL17393917 | 0.72 | HSD11B1 (0.54) | CA1CA2CA9SMN1; SMN2MEN1 | |
| SCHEMBL17394023 | 0.72 | POLB (0.44) | CA1CA2CA9SMN1; SMN2MEN1 | |
| SCHEMBL1367859 | 0.71 | POLB (0.57) | CA1CA2CA9LMNASMN1; SMN2 | |
| SCHEMBL12362454 | 0.70 | L3MBTL1 (0.46) | OPRL1OPRM1OPRK1C5AR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | AOC2 2547/4885CA1 4736/4885CA2 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.