Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078684 | 0.84 | HTT (0.52) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL19458019 | 0.84 | MAPT (0.41) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL266172 | 0.83 | TDP1 (0.67) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL13039993 | 0.83 | NPC1 (0.47) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL3297500 | 0.81 | NPC1 (0.46) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL4257916 | 0.81 | NPC1 (0.46) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL27588344 | 0.79 | HTT (0.47) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL13066253 | 0.78 | NPC1 (0.44) | NPC1RAB9AHTTTDP1KMT2A | |
| SCHEMBL1530038 | 0.78 | HTT (0.76) | NPC1RAB9AHTTKMT2AHSP90AA1 | |
| SCHEMBL12648508 | 0.78 | NPC1 (0.55) | NPC1RAB9AHTTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | MICROMIDAS, INC. (US) | 2017-03-23 | — | — | US | disclosed |
| US-7825237-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | Life Technologies Corporation (US) | 2010-02-04 | — | — | US | disclosed |
| US-7399854-B2 | Regents labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | NPC1 2513/4885RAB9A 3762/4885HTT 2574/4885 |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | SOAT1, GFPT1, CBR3 | NPC1 1676/4885RAB9A 2564/4885HTT 3017/4885 |
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | HDHD5, HPD, DCXR | NPC1 3798/4885RAB9A 4713/4885HTT 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.