Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | SNCA | P37840 | 3/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13081089 | 0.88 | MAPT (0.60) | MAPTKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL13081135 | 0.81 | APP (0.70) | MAPTKMT2AAPPSNCACCNB2 | |
| SCHEMBL14713042 | 0.78 | XDH (0.69) | MAPTKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL3798471 | 0.74 | APP (0.74) | MAPTKMT2AAPPSNCAMEN1 | |
| SCHEMBL3798469 | 0.74 | APP (0.74) | MAPTKMT2AAPPSNCAMEN1 | |
| SCHEMBL13081090 | 0.74 | APP (0.74) | MAPTKMT2AAPPSNCAMEN1 | |
| SCHEMBL23978857 | 0.73 | SOS1 (1.00) | MAPTKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL31741909 | 0.73 | SOS1 (1.00) | MAPTKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL17762647 | 0.73 | SOS1 (1.00) | MAPTKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL3745130 | 0.71 | RPS6KA3 (0.71) | MAPTAPPSNCAXDHRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298376-A1 | USE OF NOVEL NEUROPROTECTIVE 3-SUBSTITUTED INDOLONE COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298376-A1 | USE OF NOVEL NEUROPROTECTIVE 3-SUBSTITUTED INDOLONE COMPOSITIONS | NLN, HTT, PARK7 | MAPT 59/4885KMT2A 3886/4885ALDH1A1 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.