Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | MYLK | Q15746 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648491 | 0.83 | IDO1 (0.44) | TDP1PDK2FFAR1PRKCEMYLK | |
| SCHEMBL29618445 | 0.82 | CYP4F2 (0.43) | TDP1PDK2FFAR1CYP4F2CYP4A11 | |
| SCHEMBL3150243 | 0.82 | CYP4F2 (0.43) | TDP1PDK2FFAR1CYP4F2CYP4A11 | |
| SCHEMBL18382507 | 0.82 | GABRA1 (0.43) | TDP1PDK2FFAR1CYP4F2CYP4A11 | |
| SCHEMBL29534868 | 0.81 | TDP1 (0.55) | TDP1FFAR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL31203 | 0.81 | TDP1 (0.55) | TDP1FFAR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL12727308 | 0.80 | PDK2 (0.35) | TDP1PDK2FFAR1CYP4F2CYP4A11 | |
| SCHEMBL8439589 | 0.80 | ADRA2A (0.47) | PDK2FFAR1IDO1MEN1ALDH1A1 | |
| SCHEMBL21482586 | 0.77 | TRPA1 (0.37) | PDK2FFAR1CYP4F2CYP4A11MTNR1A | |
| Phenol SCHEMBL4103629 | 0.77 | TDP1 (0.52) | TDP1PDK2FFAR1PRKCEMYLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283339-B2 | Vinyl phosphonate lysophosphatidic acid receptor antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-08-06 | — | — | US | disclosed |
| WO-2008014286-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR4, LPAR5 | TDP1 4090/4885PDK2 2831/4885FFAR1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.