SCHEMBL13084948

SCHEMBL13084948

NC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.32
ADRA1D P25100 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MALT1 Q9UDY8 3/20 0.32
TRPV1 Q8NER1 1/20 0.32
SLC2A1 P11166 2/20 0.32
SLC2A3 P11169 2/20 0.32
SLC2A4 P14672 2/20 0.32
SLC2A2 P11168 1/20 0.32
NTRK1 P04629 5/20 0.31
GRM2 Q14416 1/20 0.30
CAPN1 P07384 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085438 0.94 DHODH (0.32) DHODHADRA1DALDH1A1SMN1; SMN2NTRK1
SCHEMBL13085015 0.94 ADRA1D (0.31) DHODHADRA1DALDH1A1SMN1; SMN2NTRK1
SCHEMBL685546 0.93 SLC2A1 (0.35) DHODHADRA1DALDH1A1SMN1; SMN2MALT1
SCHEMBL31060080 0.93 SLC2A1 (0.35) DHODHADRA1DALDH1A1SMN1; SMN2MALT1
SCHEMBL15489007 0.93 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1TRPV1
SCHEMBL13084972 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1TRPV1
SCHEMBL13084826 0.90 ALDH1A1 (0.34) DHODHALDH1A1SMN1; SMN2TRPV1NTRK1
SCHEMBL13085064 0.90 DHODH (0.33) DHODHALDH1A1SMN1; SMN2TRPV1NTRK1
SCHEMBL13085066 0.90 DHODH (0.34) DHODHALDH1A1SMN1; SMN2TRPV1NTRK1
SCHEMBL13084825 0.89 CRHR1 (0.39) NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885ADRA1D 2717/4885ALDH1A1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.