SCHEMBL13085152

SCHEMBL13085152

Cc1cc(C#N)cc(C(=O)NCC2CC2)c1NC(=O)c1cc(Cn2nnc(C(F)(F)C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.35
SLC2A1 P11166 3/20 0.33
SLC2A3 P11169 3/20 0.33
SLC2A4 P14672 3/20 0.33
SLC2A2 P11168 1/20 0.33
CETP P11597 2/20 0.32
LDHA P00338 1/20 0.32
CRHR1 P34998 2/20 0.31
NTRK1 P04629 2/20 0.31
CNR2 P34972 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
KLKB1 P03952 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085497 0.95 P2RX7 (0.35) P2RX7SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13084936 0.95 P2RX7 (0.35) P2RX7SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085014 0.93 P2RX7 (0.36) P2RX7CRHR1NTRK1CNR2CHRM2
SCHEMBL13084982 0.92 P2RX7 (0.40) P2RX7SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085211 0.92 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10083629 0.92 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL686718 0.91 CRHR1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CRHR1
SCHEMBL10083626 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13084846 0.90 RORC (0.34) SLC2A1SLC2A3SLC2A4SLC2A2CRHR1
SCHEMBL10083628 0.89 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 P2RX7 288/4885SLC2A1 2324/4885SLC2A3 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.