SCHEMBL13085263

SCHEMBL13085263

CCNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC2A1 P11166 2/20 0.32
SLC2A3 P11169 2/20 0.32
SLC2A4 P14672 2/20 0.32
SLC2A2 P11168 1/20 0.32
DHODH Q02127 1/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
GCK P35557 2/20 0.31
KCNH2 Q12809 2/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
MAPK14 Q16539 1/20 0.30
GRIA2 P42262 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085295 0.95 SLC2A1 (0.32) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4
SCHEMBL13085290 0.93 PIN1 (0.33) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4
SCHEMBL13085292 0.92 KCNH2 (0.32) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4
SCHEMBL13085298 0.92 SLC2A1 (0.36) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4
SCHEMBL13085289 0.92 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2DHODHPDE4BPDE4D
SCHEMBL13085140 0.92 P2RX7 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2EGLN1
SCHEMBL13085137 0.91 SLC2A1 (0.32) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4
SCHEMBL13085273 0.91 DHODH (0.33) ALDH1A1SMN1; SMN2DHODH
SCHEMBL13085266 0.90 RORC (0.35) PDE4BMAPK14EGLN1
SCHEMBL10075525 0.89 SLC2A1 (0.35) ALDH1A1SMN1; SMN2SLC2A1SLC2A3SLC2A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 ALDH1A1 3779/4885SMN1; SMN2 3923/4885SLC2A1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.